Chloroquine 50mM in PBS, Sterile

Prepared in low endotoxin PBS and filtered through 0.22µ filter. Shipped on blue ice.

Application

DNA intercalator. Also used to increase transfection efficiency.

Biochemical Actions

Standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labeling of MRP by quinoline-based photoactive drug IAAQ (N-[4-[1-hydroxy-2-(dibutylamino)ethyl]quinolin-8-yl]-4-azidosalicylamide).

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